Quantitative Brain MRI

P 24: Evaluation of the Voxel Based Morphometry in Quantitative Analysis of Brain MRI Images

Introduction: Voxel based morphometry is a type of statistical parametric mapping that can be used to investigate the effect of diseases such as epilepsy, Alzheimer's disease and Parkinson's disease or other agent such as skills on brain structure (white matter, gray matter and cerebrospinal fluid). The aim of this study is evaluate the effectiveness of this method in detection of differen...

Brain MRI Findings in Tramadol Poisoning

Whole-brain ex-vivo quantitative MRI of the cuprizone

11 Myelin is a critical component of the nervous system and a major contributor to contrast in Magnetic Resonance (MR) images. However the precise contribution of myelination to multiple MR modalities is still under debate. The cuprizone mouse is a well established model of demyelination that has been used in several MR studies, but these have often imaged only a single slice and analysed a sma...

Quantitative and local mouse brain morphometry in longitudinal MRI studies

Introduction Brain morphometry is defined as studying the variations and changes of brain shape, which is key step in monitoring diseases. Brain morphometry is often performed by group-wise comparison between populations of diseased subjects and healthy controls. In earlier work, we presented the Moore-Rayleigh statistical test to quantify local shape differences between groups of transgenic mi...

Whole-brain ex-vivo quantitative MRI of the cuprizone mouse

11 Myelin is a critical component of the nervous system and a major contributor to contrast in Magnetic Resonance (MR) images. However the precise contribution of myelination to multiple MR modalities is still under debate. The cuprizone mouse is a well established model of demyelination that has been used in several MR studies, but these have often imaged only a single slice and analysed a sma...